RAF Typhoon jets have conducted a mission with France's air force in a joint strike against an subterranean weapons facility in Syrian territory employed by the IS group, as stated by the UK Ministry of Defence.
The site, pinpointed through surveillance, was believed to be containing munitions and bombs, the statement said, and was situated in mountainous terrain just to the north of the historic site of Palmyra in central Syria.
"Our fighter planes used Paveway IV guided bombs to target a series of access tunnels leading to the facility... early reports are that the strike was effective," the MoD said.
There was no indication of any harm to civilians in the strike late on Saturday and every plane involved returned to base without incident, the MoD added.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
IS - alternatively referred to as the so-called Islamic State - imposed jihadist rule over significant areas in Syria and Iraq before its territorial defeat in 2019.
"This strike shows the UK's leading role, and determination to work closely with allied nations, to stamp out any re-emergence of Daesh and their violent and radical beliefs in the Middle East," Britain's Defence Chief John Healey remarked.
RAF aircraft have conducted patrols over Syrian airspace to "deter any efforts to regroup" of Islamic State following its military defeat at the Baghuz confrontation in 2019, the ministry said.
"I extend gratitude to the personnel of British forces involved in this strike for their skill and their bravery," Healey said. "They were part of numerous UK service members stationed over Christmas and New Year. This action, to eliminate dangerous terrorists who threaten our way of life, highlights how our armed forces are always on standby, all year round, keeping Britain secure domestically and powerful internationally."
In December, the US military executed what it called a "large-scale strike" on Islamic State objectives in Syria, subsequent to an assault resulted in the deaths of two American soldiers and a civilian interpreter in the Palmyra area.
The U.N. says IS still has between 5,000 and 7,000 fighters in both countries.